Berberine is a natural compound found in a variety of plants such as goldenseal, barberry, and Oregon grape. It can be taken as a supplement before meals and has become increasingly popular because of its impact on health.
[1]
Some research suggests that berberine could help manage blood sugar, improve insulin sensitivity, and maybe even reduce cholesterol.
[2] It may also help the body metabolize glucose and regulate the menstrual cycles of people with polycystic ovary syndrome (PCOS), according to Vanessa Imus, RD, of Integrated Nutrition for Weight Loss in Bothell, Washington.
[3] It’s been dubbed nature’s Ozempic because it appears to affect appetite control and weight loss like the GLP-1 agonist semaglutide (Ozempic).
However, as a registered dietitian with years of experience providing nutritional guidance, I know that not all berberine supplements are created equal. To help you find the safest berberine supplements out there, I helped the Everyday Health team and six additional nutrition experts evaluate over 15 berberine supplements. Here are the ones we recommend.
Our Top Picks for Berberine Supplements
- Best for Weight Loss: SoWell Balanced
- Best for Blood Sugar Control: Now Berberine Glucose Support
- Best for Cholesterol: Thorne Berberine
- Best for Gut Health: Garden of Life Liposomal Berberine
- Best for PCOS: Pure Encapsulations Berberine UltraSorb
- Best for Heart Health: Nature’s Bounty Berberine
- Best for Inflammation: NatureBell Berberine
- Best for Immunity: Doctor Recommended Supplements Berberine Plus
- Best Budget: Horbäach Berberine Ceylon Cinnamon Complex
- Best Absorption: Nature Made Better Absorption Berberine Phytosome
- Best Vegan: NutriFlair Berberine+ With Ceylon Cinnamon